Showing posts with label lung diseases. Show all posts
Showing posts with label lung diseases. Show all posts

Thursday, February 2, 2012

Influenza Pneumonia


Description
Pneumonia is a generic term used to describe several diseases in which an infection or a chemical cause inflammation of the alveoli. These cavities are filled with fluid or pus, preventing the lungs to transfer oxygen efficiently into the bloodstream.
Before the advent of antibiotics in the 1930s, pneumonia was a leading causes of death. Although it has become easier to treat, pneumonia remains a public health problem.
Pneumonia comes in many different forms with a spectrum of severity varies widely. There are basically four types:
the community-acquired pneumonia (CAP), is the form of pneumonia the most common. It is caused by bacteria, viruses and other acquired outside a hospital or other health care settings;
pneumonia hospital (PH) or nosocomial (NP) said at least 48 hours after admission to a hospital. It can be triggered by bacteria or other organisms different from those usually are the cause of community-acquired pneumonia. Hospital pneumonia is usually more serious than community-acquired pneumonia because the presence of bacteria and organisms can make it more difficult to treat, and because it strikes people are already sick;
aspiration pneumonia is caused by the inhalation of liquids or other irritants in the lungs. Aspiration pneumonia is the most common is caused by the inhalation of the contents of the stomach after vomiting. People who have health problems (eg. A stroke, Lou Gehrig's disease) that affect swallowing are more susceptible to this type of pneumonia;
Opportunistic pneumonia reached the people who have a weakened immune system (eg. by AIDS, cancer, organ transplant). The organisms that cause these infections do not normally affect people enjoying healthy immune systems.
The healthy people aged under 65 will rarely serious complications following pneumonia. People with chronic lung disease or whose immune systems are generally at higher risk of pneumonia.


Causes
The most common causes of pneumonia are caused by infections:
bacteria - the most common cause of pneumonia in adults;
viruses - virus pneumonia especially for children;
mycoplasma - these microorganisms to the characteristics of viruses and bacteria cause less severe infections;
microorganisms opportunistic - a threat to people with weakened immune systems (eg. Pneumocystis carinii pneumonia in AIDS patients).
Most forms of pneumonia are transmitted in the same way as influenza or the common cold, that is to say by the contact of hands and by tiny droplets from the mouth and nose. In fact, the same viruses that cause colds and flu can also cause pneumonia. When these viruses infect the throat, sinuses or upper respiratory tract, it is a cold. If the virus reaches the lungs is pneumonia.

Bacteria that are present at all times in the throat (or pharynx) cause many people some of the most serious forms of pneumonia. Under normal conditions, the immune system effectively combat these bacteria. By cons, if the immune system is weakened by a virus in the pharynx, these bacteria can invade the respiratory tract. Bacterial pneumonia is most often caused by the bacterium Streptococcus pneumoniae (pneumococcus).
Most pneumonia affecting infants and young children are caused by respiratory syncytial virus (RSV). The incidence of this disease is increasing sharply in December and January, but it does not life threatening. Viruses cause about half of all cases of pneumonia.
Mycoplasmas cause a disease called "walking pneumonia", so called because the people affected are not confined to bed.
A fungus called Pneumocystis carinii is not normally found only in people with AIDS. Under normal conditions, this fungus is harmless, but in people infected with HIV, it can cause an aggressive and often fatal pneumonia.
In addition to infectious diseases, pneumonia can be caused by chemicals that enter the lungs and cause inflammation. Aspiration pneumonia is caused by accidental aspiration of food, vomiting or stomach acid into the lungs. The inhaled substance may become infected, or it may inflame the lungs and cause a consolidation (the alveoli fill with fluid).

The risk of pneumonia is higher in the following cases:
younger than 1 year or greater than 65;
smoking;
the presence of a cold or flu;
a weakened immune system due to cancer treatment, an HIV infection or other illness;
surgical treatment;
an addiction to alcohol;
a chronic condition like heart disease, lung disease or diabetes;
chronic lung disease, eg. asthma or chronic obstructive pulmonary disease.

Symptoms
Symptoms of pneumonia vary depending on its cause and the general health of the person affected.
Pneumonia always causes a cough, and it is often productive, that is to say, it is accompanied by sputum. Sputum of a reddish brown, green or yellow can be a sign of bacterial infection. Clear and whitish sputum is a possible sign of infection with a mycoplasma.
In bacterial pneumonia, the lungs, in whole or in part, slowly fill with liquid, this is called consolidation. Some bacterial lung infections settle in a few hours. There is usually a high fever that sometimes reached 40.9 ° C (105 ° F).
Here are some other possible symptoms of bacterial pneumonia:
shortness of breath;
tremors,
chills,
a headache,
delirium (the confusion),
a very bad breath,
muscle pain,
weakness,
a chest pain, especially deep breathing,
blue lips and nail beds due to lack of oxygen in the blood.
Viral pneumonia does not cause fluid accumulation in the lungs, it causes more inflammation of the lung tissue itself. It is usually less severe than bacterial pneumonia. Pneumonia caused by influenza viruses can be very serious and is an exception to this rule.
Viral pneumonia produced the characteristic symptoms include:
dry cough,
little sputum,
headaches,
muscle pain,
weakness and fatigue,
moderate fever, up to 39 ° C (102 ° F),
shortness of breath;
blue lips and nail beds.


Treatment
Bacterial pneumonia can be treated with antibiotics, as well as pneumonia caused by mycoplasma. It is extremely important to take antibiotics exactly as prescribed by your doctor and complete the full treatment, even if you feel better. There is no cure for most viral infections, we must simply wait until the body gets rid of. Your doctor will advise you on ways to relieve the symptoms of viral pneumonia. Fungal infections can be treated with antifungal medications.
There are four ways to prevent pneumonia. The first is to adopt a diet rich in fruits and vegetables, stay physically fit and get enough sleep. These measures help to preserve the strength of the immune system.
The second way is vaccination. There is no vaccine against most forms of pneumonia, but the two most common forms are preventable with vaccines: a vaccine against the flu virus and the vaccine against pneumococcus. In Canada, it is recommended that the entire population be vaccinated against influenza each year. In some provinces, influenza vaccine is administered free of charge. In addition, a new vaccine against pneumococcus has been developed to protect children against Streptococcus pneumoniae and is now recommended as part of the primary vaccination in infants.
The third way to prevent pneumonia is to consult the doctor when coughing continues to deteriorate after three or four days. Consult your doctor immediately if your sputum contains blood or have an unusual color or smell. While the initial disease was a common cold, bacteria can easily cause a secondary infection resulting in a severe pneumonia.
The fourth way to prevent the spread of viruses and bacteria that can cause pneumonia is to wash your hands thoroughly and frequently.


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Sunday, January 29, 2012

Lung Cancer




Description

A greater number of men and women, generally aged 65 to 75, dying of lung cancer than any other cancer.

The majority of lung cancer develops in the bronchi, that is to say, in the upper airway leading to the lungs. There are different types of lung cancer. The most common is lung cancer "non-small cell", which includes adenocarcinoma, large cell carcinoma and squamous cell carcinoma. The other type of lung cancer is that of small cell carcinoma (or carcinoma cells "oat").

Each category is evolving at a different rate and responds differently to treatment. Most lung cancers are smoking related, with the exception of adenocarcinoma. Often as a head cancer in other parts of the body spreads to the lungs.

Causes

Smoking is the main risk factor for lung cancer, and is the cause of over 80% of lung cancers. The more a person has smoked for a long time and she smokes, the greater her risk of lung cancer. If you quit smoking before cancer develops, the lung tissue damage caused by smoking begin to heal. The risk of cancer for an ex-smoker will not be as weak as a person who never smoked, but it still will fall over time. The use of the cigar and pipe smoking causes almost the same degree of risk of lung cancer as cigarette smoking.

Even second-hand smoke, that is to say that a person inhales the smoke in the presence of smoking can cause lung cancer. Non-smokers whose spouse smokes are at higher risk of 30% of suffering from lung cancer than the spouse of a person who does not smoke.

Living in an environment where the air is heavily polluted, or having a job that requires handling of radioactive minerals or asbestos can also increase the risk of lung cancer. The research to better understand how these risk factors produce certain changes in DNA in the cells of the lung. These changes induce abnormal growth of cells and the formation of cancerous tumors.

DNA is the genetic material that contains instructions for all cell functions, or almost. Some genes (that is to say parts of the DNA) regulate growth and cell division. The risk factors that we described earlier can trigger changes, also known as mutations of these genes, which will then cause the development of cancer. Moreover, the risk of suffering from certain forms of cancer (eg. Breast cancer, ovarian, colorectal cancer, and many others) can be hereditary. However, scientists believe that in many lung cancer, heritable genetic mutations do not cause cancer.

Symptoms and Complications

The first symptom, and the most common lung cancer is coughing. When chronic bronchitis is followed by lung cancer, cough caused by bronchitis worse. Cancer cells can develop in blood vessels, which results in the presence of blood in the sputum (secretions coughed up). Cancer can still develop at the expense of the bronchi or put pressure on them, reducing their diameter and cause wheezing. Cancer can also develop in the chest wall and cause chest pain. The tumor can also cause pneumonia, which is accompanied by cough, fever, chest pain and shortness of breath. People with lung cancer have more advanced stage of appetite, are weakened and lose weight.

Lung cancer can invade adjacent tissues to the lungs or other distant tissues such as liver, brain and bones, which also causes pain. The tumor may also develop in a vein that carries blood from the upper body to the heart, and the block. This condition, called compression syndrome of the superior vena cava, is characterized by the reflux of blood in the veins of the face, neck and upper chest and swelling of the veins.

Cancer can cause fluid accumulation in the envelopes of the heart or lungs, making breathing very difficult. Cancer cells sometimes exert pressure on the lung and may crush it (collapse) when the tumor presses on the spinal cord, the patient feels pain or has a disorder of nerve function. Some cancers produce more hormones that affect metabolism.

Diagnosis

In general, the doctor suspects a lung cancer when chest radiograph showed a shadow on a lung. To confirm the diagnosis, the doctor makes analyzing sputum. Your doctor may confirm the lesion with a CT scan of the chest and use this image to take a biopsy (a sample) of the lesion using a long needle inserted into the chest cavity.

Usually, doctors use a device to directly observe the bronchi: the bronchoscope is introduced into the trachea into the bronchi. This examination is called bronchoscopy. A biopsy can also be performed during bronchoscopy. This process involves taking a sample of tumor tissue for examination under a microscope later. A surgeon can also take a sample of tissue during surgery, after an incision in the chest.
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Pleural Mesothelioma


from wikipedia
Mesothelioma is a malignant tumor of the mesothelium, envelope consists of two layers between which is a lubricating fluid. The mesothelium surrounding many organs: it called for the lung pleura, peritoneum for digestive viscera, pericardium to the heart.

The most common is that of the pleura: pleural mesothelioma is

It is almost always secondary to the inhalation of asbestos dust (this is known since the 60s) and possibly some RCFs. Microfibers inhaled asbestos will be housed deep within the respiratory tree in the cells, these high strength fibers migrate to the pleura where mechanical irritation of the pleura, the lesion base is primarily physical, not chemical. The time between exposure and disease, often by several decades, but may be shorter in some cases. This exposure can be short (one or two years) and therefore difficult to find and prove 40 or 50 years later.

Mesothelioma is one of the pathologies induced by asbestos (see our article on the subject)

Smoking increases the risk of lung injury but does not affect the risk of developing mesothelioma.

The signs of the disease are not very evocative and often late: Chest pain, neuralgia in the arm, back pain in the shoulder blade. Therefore considered to be rather banal
More evocative: pleural effusion (fluid between the often bloody layers of the pleura) with dyspnea (breathlessness)

The chest X-ray is rarely helpful except at an advanced stage.
Microscopic examination of aspirated fluid if effusion malignant cells can be found
CT and MRI examinations are the most useful and the diagnosis will be confirmed by a biopsy of the pleura or by thoracoscopy

Treatment: early surgery may be successful, then radiation therapy may slow the progression finally chemotherapy will be only palliative. The prognosis is generally awful (one year survival in many cases only).

Prevention is essential: removal of sprayed asbestos, protection of workers and their families (wife who cleans clothes for example)
Asbestos is banned in France since 1997 and in many Western countries (but there are other countries where everything needs to be done ...)

Occupations exposed are numerous.
Those who pay the highest price were, are and will (if the maximum is expected between 2010 and 2020):

Plumbers, welders, pipe fitters
Workers in the construction of iron or steel (carpenters, shipbuilding and rail car)
Sheet metal workers, boilermakers, auto mechanics and truck
Electricians
Construction workers in general
DIYers "madmen"
Employment in the manufacture of articles containing asbestos (asbestos cement, asbestos textile industry until 1996 with activity of carding, spinning or weaving)
Employment in the insulation (thermal or acoustic), in the manufacture of electrical insulators in power plants, refineries
Automotive repair and other vehicles (brake and clutch)
Assemblers in ventilation / heating / cooling, boiler installer
Steel industry (blast furnaces, coke ovens, steel mills)
Glass Industry
Dockers
And so on. ...

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